Megalin and cubilin are two large endocytic membrane receptors expressed in several tissues but with the highest expression in the renal proximal tubule. The two receptors mediate the endocytic uptake of a large number of substances filtered in the renal glomeruli including proteins, vitamins and trace elements bound to their carrier proteins.
CITATION STYLE
Birn, H., Leboulleux, M., Moestrup, S. K., Ronco, P. M., Aucouturier, P., & Christensen, E. I. (2003). Megalin, cubilin and immunoglobulin light chains: receptor-mediated uptake of light chains in kidney proximal tubule. In Monoclonal Gammopathies and the Kidney (pp. 37–48). Springer Netherlands. https://doi.org/10.1007/978-94-017-0191-4_4
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