The in vivo anti-tumor activities of decursinol angelate (1) and decursin (2) isolated from the roots of Angelica gigas were investigated. These two compounds, when administered consecutively for 9 days at 50 and 100 mg/kg i.p. in mice, caused a significant increase in the life span and a significant decrease in the tumor weight and volume of mice inoculated with Sarcoma-180 tumor cells. These results suggest that decursinol angelate (1) and decursin (2) from A. gigas have anti-tumor activities.
CITATION STYLE
Lee, S., Yeon, S. L., Sang, H. J., Kuk, H. S., Kim, B. K., & Sam, S. K. (2003). Anti-tumor activities of decursinol angelate and decursin from Angelica gigas. Archives of Pharmacal Research, 26(9), 727–730. https://doi.org/10.1007/BF02976682
Mendeley helps you to discover research relevant for your work.