Gut microbiota-host lipid crosstalk in Alzheimer’s disease: implications for disease progression and therapeutics

6Citations
Citations of this article
43Readers
Mendeley users who have this article in their library.

This article is free to access.

Abstract

Trillions of intestinal bacteria in the human body undergo dynamic transformations in response to physiological and pathological changes. Alterations in their composition and metabolites collectively contribute to the progression of Alzheimer’s disease. The role of gut microbiota in Alzheimer’s disease is diverse and complex, evidence suggests lipid metabolism may be one of the potential pathways. However, the mechanisms that gut microbiota mediate lipid metabolism in Alzheimer’s disease pathology remain unclear, necessitating further investigation for clarification. This review highlights the current understanding of how gut microbiota disrupts lipid metabolism and discusses the implications of these discoveries in guiding strategies for the prevention or treatment of Alzheimer’s disease based on existing data.

Cite

CITATION STYLE

APA

Luo, Y. X., Yang, L. L., & Yao, X. Q. (2024, December 1). Gut microbiota-host lipid crosstalk in Alzheimer’s disease: implications for disease progression and therapeutics. Molecular Neurodegeneration. BioMed Central Ltd. https://doi.org/10.1186/s13024-024-00720-0

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free