The emerging role of the TGFβ tumor suppressor pathway in pancreatic cancer

13Citations
Citations of this article
14Readers
Mendeley users who have this article in their library.

This article is free to access.

Abstract

Pancreatic adenocarcinoma is one of the most aggressive human cancers. It displays many different chromosomal abnormalities and mutations. To design new therapeutic strategies, it is important to identify the signaling pathways and gene networks within this apparent complexity that are predominantly altered. The TGFβ signaling pathway and associated transcription network emerges as a central actor of pancreatic oncogenesis. Its tumor suppressor function in this tissue can be affected by several alterations. © 2012 Landes Bioscience.

Cite

CITATION STYLE

APA

Birnbaum, D. J., Mamessier, E., & Birnbaum, D. (2012, February 15). The emerging role of the TGFβ tumor suppressor pathway in pancreatic cancer. Cell Cycle. Taylor and Francis Inc. https://doi.org/10.4161/cc.11.4.19130

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free