Gene ontology analysis on behalf of improved classification of different colorectal cancer stages

Abstract

The colorectal cancer is a serious cause of death worldwide. Diagnosing the current colorectal cancer stage is crucial for early prognosis and adequate treatment of the patients. Even though the scientists have developed various techniques, determining the real colorectal cancer stage is still critical. In this paper we utilize Gene Ontology analysis information to address this issue. We compose a set of special genes that are used to obtain two main results—we show the distinction between the carcinogenic and healthy tissue by difference in the range of their DNA gene expressions, and we propose a novel methodology that improves the colorectal cancer stages classification..