Función renal, estado de volemia y furosemida en diálisis peritoneal

Abstract

The main object was to compare diuresis and renal function in peritoneal dialysis incident patients and their evolution according to the use of furosemide. The secondary object was to evaluate whether furosemide can improve the volume status. Material and methods: A multicentre, longitudinal, comparative, retrospective study was carried out. The sample was 40 patients. In one unit diuretics (furosemide group) were used and in another they were not (control group). Study variables were noted at the start, and after 6 and 12 months. The analysis was carried out using SPSS 19. Results: 57.5% of the patients were men. The average age was 56.45 ± 16.2 yeas. The most prevalent aetiology was interstitial nephritis. No patients presented side effects. The evolution of diuresis was the same in both groups, and was higher in the furosemide group without significance. We did not find significant differences throughout the study for diuresis, glomerular filtration, weight, body mass index and mean ultrafiltration. 40% of the patients in the control group presented oedemas after 6 months compared to 17.6% in the furosemide group. The control group used a larger number of hypertonic exchanges during the first year. The furosemide group showed higher systolic and diastolic blood pressure and used more hypotensors, although without significance. Conclusions: The administration of low doses of diuretics has not shown significant differences for diuresis and renal functions during the first year on peritoneal dialysis. Perhaps on account of the low doses, the use of diuretics did not improve the parameters related to the volume status.