The nucleotide sequence of 1100bp around the origin of replication of the pSC101 plasmid has been determined. This segment of DNA is capable of replication in the presence of a helper plasmid. The sequence data reveal similarities between pSC101 and several other replicons. The origin of replication contains three direct repeats of an 18bp sequence associated with a segment exceptionally rich in A-T base pairs. A promotor that probably directs transcription of a gene encoding an essential plasmid replication function is associated with a region of extensive potential secondary structure. The sequence presented here includes the sequence of the par region involved in partitioning of plasmids at cell division. © 1983 IRL Press Limited.
CITATION STYLE
Churchward, G., Linder, P., & Caro, L. (1983). The nucleotide sequence of replication and maintenance functions encoded by plasmid PSCl0l. Nucleic Acids Research, 11(16), 5645–5659. https://doi.org/10.1093/nar/11.16.5645
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