Application of graphene FET nucleic acid biosensor in human motion measurement

Abstract

In order to explore the application of graphene field effect transistor (FET) nucleic acid biosensor, the sensitivity and selectivity of nano FET biosensor detection are improved by the large physical surface ratio, high electron mobility, excellent thermo conductivity and high mechanical strength. The nano-material graphene is applied to the field effect transistor biosensor, and the FET biosensor based on graphene is constructed. In addition, target molecules with specific probes are immobilized on the surface of graphene. The purpose of detecting nucleic acid molecules with high sensitivity and high selectivity can be achieved by detecting the change of electrical signals before and after hybridization and using nucleic acid - nucleic acid molecules hybridization. At the same time, the DNA biosensor can be reused. The reduced graphene oxide (R-GO) field effect transistor DNA biosensor constructed has high sensitivity, high selectivity and reusability. The research results showed that it has a potential application prospect in human motion measurement as a detection tool. To sum up, graphene FET nucleic acid biosensor is suitable for being used in human motion measurement.