Magnetic and flow cytometry-based methods were used to characterize clonogenic stromal cells in human bone marrow. STRO-1bright stromal cells were found to lack expression of CD34, CD45 and glycophorin-A markers associated with hematopoietic progenitor cells. These studies support the view that these are two distinct stem cell compartments in adult bone marrow.
CITATION STYLE
Zannettino, A. C. W., Paton, S., Kortesidis, A., Khor, F., Itescu, S., & Gronthos, S. (2007). Human multipotential mesenchymal/stromal stem cells are derived from a discrete subpopulation of STRO-1bright,/CD34-/CD45 -/glycophorin-A- bone marrow cells. Haematologica, 92(12), 1707–1708. https://doi.org/10.3324/haematol.11691
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