Are all intracranial mass lesions always a contraindication for thrombolytic therapy?

Abstract

Thrombolytic therapy is regarded as the first treatment choice in haemodynamically unstable patients with pulmonary embolism. Intracranial tumors have long been considered as a contraindication to thrombolytic therapy due to the risk of intracerebral haemorrhage. In this report, we presented a 76-year-old female patient with meningioma and massive pulmonary embolism who had received thrombolytic therapy despite a contraindication of intracranial mass. The patient completed the thrombolytic therapy without having complication.