While numerous cases of immediate-type occupational asthma due to persulfates with positive skin prick test reactions to ammonium persulfate are well documented, few non-immediate type reactions have been described in the literature. We report the case of an atopic worker who developed work-related asthmatic symptoms shortly after he began his job in persulfate production. The diagnosis of asthma was corroborated by methacholine testing. The patient showed a positive patch test reaction to ammonium persulfate, while skin prick test was negative. He presented an isolated late symptomatic airway obstruction after a cumulative dose of 0.6 mg ammonium persulfate administered by a dosimeter method. An immunologic mechanism was demonstrated by a significant increase in exhaled nitric oxide and the number of eosinophils in induced sputum. These findings suggest that isolated late bronchial reactions to persulfates are mediated by eosinophilic inflammatory responses. © Springer Science+Business Media Dordrecht 2013.
CITATION STYLE
Polychronakis, I., Thanasias, E., Raulf-Heimsoth, M., & Merget, R. (2013). Occupational non-immediate type allergic asthma due to ammonium persulfate. In Advances in Experimental Medicine and Biology (Vol. 755, pp. 79–84). Springer Science and Business Media, LLC. https://doi.org/10.1007/978-94-007-4546-9_10
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