In this chapter, we discuss de-esclation of treatment for patients with HPV-positive disease. We discuss the rationale for de-escalation (why de-escalate?), patient selection criteria (who to de-esclate?) and what the treatment options for de-esclation are and the studies that are currently being run in those areas (how to de-escalate?). We stress the importance of clinicians NOT changing the management of oropharyngeal cancer patients outside clinical trials, and encourage them to recruit to the ongoing studies.
CITATION STYLE
Mehanna, H. (2017). Update on de-intensification and intensification studies in HPV. In Recent Results in Cancer Research (Vol. 206, pp. 251–256). Springer New York LLC. https://doi.org/10.1007/978-3-319-43580-0_20
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