Cyclosporine-A therapy-induced multiple bilateral breast and accessory axillary breast fibroadenomas: A case report

Abstract

Introduction. Breast adenoma is common. However, in the setting of post-transplantation immune suppression it may be expressed differently. Case presentation. A 35-year-old Sudanese woman, with a history of renal transplantation two and half years prior to presentation, was on a single immune suppression therapy in the form of cyclosporine-A since the transplantation. During a regular follow-up visit, she was noticed to have gingival hypertrophy and bilateral breast and axillary swellings. She underwent successful surgical resection of the bilateral fibroadenomas. Conclusions: Cyclosporine-A therapy post renal transplantation is associated with an increased incidence of benign breast changes as fibroadenoma. Regular follow-up and appropriate selection of immunosuppressant therapy are essential in the post transplantation management of these patients. © 2010 Darwish et al; licensee BioMed Central Ltd.