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Long-Lasting Behavioural Changes after a Single Footshock Stress Session. A Model of Depression?

  • van Dijken H
  • van der Heyden J
  • Mos J
  • et al.
Birkhäuser Basel, (1991), 231-236
DOI: 10.1007/978-3-0348-6419-0_22
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Abstract

Exposure of male rats to a single brief period of footshocks lnduced behavioural changes as measured in the open field test that lasted for at least 3 weeks. Moreover, such rats showed a long-Iasting increased responsiveness to a sudden change in environmental stimuli. These effects of footshock exposure are probably useful as an animal model of depression.

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van Dijken, H. H., van der Heyden, J. A. M., Mos, J., & Tilders, F. J. H. (1991). Long-Lasting Behavioural Changes after a Single Footshock Stress Session. A Model of Depression? In Animal Models in Psychopharmacology (pp. 231–236). Birkhäuser Basel. https://doi.org/10.1007/978-3-0348-6419-0_22

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