Increasing infections with Monkeypox and Cowpox viruses pose a continuous and growing threat to human health. The standard method for detecting poxvirus neutralizing antibodies is the plaque-reduction neutralization test that is specific but also time-consuming and laborious. Therefore, a rapid and reliable method was developed to determine neutralizing antibody titers within twelve hours. The new assay measures viral mRNA transcription as a marker for actively replicating virus after incomplete neutralization using real-time PCR. © 2011 Kramski et al; licensee BioMed Central Ltd.
CITATION STYLE
Kramski, M., Drozd, A., Lichtfuss, G. F., Dabrowski, P. W., & Ellerbrok, H. (2011). Rapid detection of anti-Vaccinia virus neutralizing antibodies. Virology Journal, 8. https://doi.org/10.1186/1743-422X-8-139
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