Medicinal Plant Based Advanced Drug Delivery System for the Treatment of Chronic Lung Diseases

Abstract

Chronic pulmonary diseases such as bronchial asthma, chronic obstructive pulmonary disease, pulmonary fibrosis, cystic fibrosis, and lung cancers represent the major health issues in both developing and developed countries. Till now various synthetic molecules are used to treat a wide range of pulmonary diseases. But due to some life-threatening side effects of the synthetic molecules, natural phytoconstituents or plant antibiotics are preferred as they have minimal side effects and efficient therapeutic outcomes. Though the drug delivery system used for administering the phytoconstituents so far is out of date, resulting in reduced efficacy of the drugs. So if the novel drug delivery system is used for the administration of herbal medicine, one may get improved results. Further introduction of a novel drug delivery system limits various drawbacks of traditional drug delivery systems. The advanced drug delivery system such as nanotechnology, oligonucleotides based systems, and other novel drug delivery system improves the pharmacokinetics of the drugs. For instance, nano-based systems such as liposomes, polymeric nanoparticles are designed to improve the bioavailability and stability of phytoconstituents used in chronic conditions such as lung cancer. Thus integration of novel drug delivery systems and herbal medicines proves to be an effective measure in combating serious chronic lung diseases.