Graphene oxide supported palladium nanoparticle as an electrochemical sensor for epinephrine

Abstract

The electrochemical performance of palladium incorporated reduced graphene oxide glassy carbon electrode (rGO/Pd/GCE) towards epinephrine (EP) was studied. Modification of GCE with nanocomposite was confirmed using electrochemical techniques such as cyclic voltammetry (CV) and differential pulse voltammetry (DPV) and it was found that the electrochemistry of EP was greatly enhanced. Studies reveal that the oxidation of EP occurs by a diffusion controlled process. Oxidation peak currents of EP exhibited good linearity with the concentration range 1 μM - 10 μM with a very low detection limit of 30 nM. The interference study with DPV showed clear peak separation for uric acid (UA) and EP, which has great relevance in biological systems. Thus the modified electrode can selectively detect EP in presence of UA.