Abstract
The construction of the fragments C1-C9 3 and C17-C27 4a of the bryostatins in a enantioselective and highly diastereoselective fashion is described. The usefulness of the "chiron" approach is illustrated with the synthesis of these fragments from respectively D-pantolactone (6) and D-isobutyl lactate (14) as chiral templates.
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CITATION STYLE
APA
De Brabander, J., & Vandewalle, M. (1996). Towards the asymmetric synthesis of bryostatin 1. Pure and Applied Chemistry, 68(3), 715–718. https://doi.org/10.1351/pac199668030715
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