Two Novel Lipophilic Antioxidants Derivatized from Curcumin

1Citations
Citations of this article
10Readers
Mendeley users who have this article in their library.

Abstract

Tert-butyl curcumin (TBC), demethylated tert-butylated curcumin (1E,6E-1,7-bis(3-tert-butyl-4,5-dihydroxyphenyl)hepta-1,6-diene-3,5-dione, DMTC), demethylated curcumin (DMC), and Cur were synthesized from the starting compound, 2-methoxy-4-methylphenol. TBC and DMTC are two novel lipophilic compounds, and Cur and DMC are polar and hydrophilic. The an-tioxidant activities of Cur, TBC, DMC, and DMTC were evaluated by using the methods of 2,2- diphenyl-1-(2,4,6-trinitro-phenyl)-hydrazinyl (DPPH), deep-frying, and Rancimat. Tert-butylhydro-quinone (TBHQ) and Butylated hydroxytoluene (BHT) were used as comparison compounds. Both Rancimat and deep-frying tests demonstrated that DMTC was the strongest antioxidant, and TBC also had stronger antioxidant activity than Cur. In the DPPH assay, DMC showed the highest scavenging activity, followed by DMTC, TBHQ, Cur, and TBC. DMTC and TBC can be potentially used as strong antioxidants in food industry, especially for frying, baking, and other high temperature food processing. DMTC is the strongest antioxidant in oil to our knowledge.

Cite

CITATION STYLE

APA

Liu, T., Liu, X. H., Olajide, T. M., Xu, J., & Weng, X. (2022). Two Novel Lipophilic Antioxidants Derivatized from Curcumin. Antioxidants, 11(4). https://doi.org/10.3390/antiox11040796

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free