Structural biology of programmed cell death

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Abstract

Structural and biochemical characterization on death receptors, Bcl-2 family proteins, caspases, IAPs, Smac/DIABLO, and other regulatory proteins has revealed significant insights into the molecular mechanisms of apoptosis. This chapter summarizes these advances and presents our current understanding of apoptosis from a structural and mechanistic perspective.

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Shi, Y. (2009). Structural biology of programmed cell death. In Essentials of Apoptosis: A Guide for Basic and Clinical Research (pp. 95–118). Humana Press Inc. https://doi.org/10.1007/978-1-60327-381-7_4

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