A bioimpedance-based cardiovascular measurement system

Abstract

Bioimpedance measurement is a biomedical technique to determine the electrical behavior of living tissue. It is well known for estimating the body composition or for the electrical impedance tomography. Additionally to these major research topics, there are applications with completely different system requirements for the signal acquisition. These applications are for example respiration monitoring or heart rate measurements. In these cases, very high resolution bioimpedance measurements with high sample rates are necessary. Additionally, simultaneous multi-channel measurements are desirable. This work is about the hardware and software development of a 4-channel bio-impedance measurement system, whereat all channels are galvanically decoupled from each other. It is capable of measuring 1000 impedance magnitudes per second and per channel. Depending on the chosen measurement configuration, impedance changes down to mΩ ranges are feasible to be detected. To enable the usage in a variety of different research applications, further biosignals like photoplethysmography, electrocardiography or heart sounds can be acquired simultaneously. For electrical safety purposes, an implemented galvanically isolated USB interface transmits the data to a host PC. The impedance measurements can be analyzed in real-time with a graphical user interface. Additionally, the measurement configuration can easily be changed via this GUI. To demonstrate the system’s usability, exemplary measurements from human subjects are presented.