Exploring the phytochemicals of acacia melanoxylon R. Br

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Abstract

Invasive species are currently a world menace to the environment, although the study of their chemistry may provide a means for their future beneficial use. From a study of Portuguese Acacia melanoxylon R. Br. five known compounds were isolated: lupeol, 3β-Z-coumaroyl lupeol, 3β-E-coumaroyl lupeol (dioslupecin A), kolavic acid 15-methyl ester and vomifoliol (blumenol A). Their structures were elucidated by 1D and 2D NMR spectroscopy and mass spectrometry, and as a result some corrections are made to their previous13 C NMR assignments. Cytotoxicity of 3β-E-coumaroyl lupeol (dioslupecin A) and kolavic acid 15-methyl ester was evaluated against HCT116 human colorectal cancer cells although biological activity was not evident.

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Alves, D., Duarte, S., Arsénio, P., Gonçalves, J., Rodrigues, C. M. P., Lourenço, A., & Máximo, P. (2021). Exploring the phytochemicals of acacia melanoxylon R. Br. Plants, 10(12). https://doi.org/10.3390/plants10122698

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