Systemic lupus erythematosus associated with sickle-cell disease: A case report and literature review

Abstract

Introduction. The occurrence of systemic lupus erythematosus has been only rarely reported in patients with sickle-cell disease. Case presentation. We describe the case of a 23-year-old North-African woman with sickle-cell disease and systemic lupus erythematosus, and discuss the pointers to the diagnosis of this combination of conditions and also present a review of literature. The diagnosis of systemic lupus erythematosus was delayed because our patients symptoms were initially attributed to sickle-cell disease. Conclusions: Physicians should be alerted to the possible association of sickle-cell disease and systemic lupus erythematosus so as not to delay correct diagnosis and initiation of appropriate treatment. © 2012 Maamar et al.; licensee BioMed Central Ltd.