Studies on Quantitative Structure-Activity Relationships. V. QSAR Investigations of Rifamycin B Amides and Hydrazides by Utilization of the Substituent Entropy Constant σ s°

Abstract

QSAR analyses of rifamycin B amides and hydrazides were carried out, and the following equations containing the substituent entropy constant, σs°, were obtained (the subscripts 1, 2 and 3 denote the substituent groups on the nitrogen atom). © 1983, The Pharmaceutical Society of Japan. All rights reserved.