Size of continuous curvilinear capsulorhexis for prevention of PCO

Abstract

Several systemic and ocular associations have been cited as influencing the development of posterior capsule opacification (PCO). Surgical methods such as the size of CCC, in-the-bag IOL implantation, and sealed capsule irrigation also can influence the formation of PCO. Size of the CCC is discussed in this chapter. Between large and small capsulorhexis, significantly greater wrinkling of the posterior capsule and worse posterior capsular opacification are seen in the large capsulorhexis group than with small capsulorhexis group. Visual acuity is worse with large capsulorhexis. Both equatorial and anterior capsule lens epithelial cells are important in the production of posterior capsular opacification, and their relative contribution depends on the relationship of the anterior capsule edge to the lens optic. A well-centered capsulorhexis smaller than the lens optic is preferable to a large capsulorhexis, so that the edge lies completely on the surface of the implant.