Total synthesis of palau'amine

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Abstract

(Figure Presented) Worth the wait: The long anticipated total synthesis of palau'amine has been accomplished by a route featuring highly chemoselective transformations, cascade reactions, and a remarkable transannular cyclization to secure the unprecedented trans-5,5 ring junction (shown in red). © 2010 Wiley-VCH Verlag GmbH & Co. KGaA.

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Seiple, I. B., Su, S., Young, I. S., Lewis, C. A., Yamaguchi, J., & Baran, P. S. (2010). Total synthesis of palau’amine. Angewandte Chemie - International Edition, 49(6), 1095–1098. https://doi.org/10.1002/anie.200907112

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