Shedding of Herpes Simplex Virus Type 1 into Saliva after Surgery for Oral and Genital or Urological Cancer Patients

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Abstract

The shedding of herpes simplex virus type-1 (HSV-1) into the saliva was compared in 28 patients with oral cancer and 26 patients with genital or urological cancer. All subjects tested positive for HSV-1 specific antibody. A statistically significant (p<0.001) difference was found: infectious viruses were isolated from 12 (39.8%) of the oral cancer patients versus only 2 (7.6%) of the genital or urological patients. This indicates that direct stimulation of peripheral nerves during surgery was responsible for the greater reactivation of HSV-1. © 1989, Kurume University School of Medicine. All rights reserved.

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APA

Kameyama, T., Haikata, K., Nakamura, Y., Murase, H., & Yamamoto, S. (1989). Shedding of Herpes Simplex Virus Type 1 into Saliva after Surgery for Oral and Genital or Urological Cancer Patients. The Kurume Medical Journal, 36(3), 117–121. https://doi.org/10.2739/kurumemedj.36.117

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