Lp-PLA2, a Novel Potential Biomarker Predicting Cardiovascular Disease in Type 2 Diabetes Mellitus

Abstract

Cardiovascular disease (CVD) is the fatal complication of diabetes mellitus and it is a large economic burden of the world. Although there are a few biomarkers in predicting the cardiovascular disease, the disease is still far from being diagnosed and evaluated precisely in type 2 diabetes mellitus (T2DM) patients. Lp-PLA2 takes part in several links of the pathological mechanism in the diabetic cardiovascular disease. Researches have implied that the Lp-PLA2 has positive association with CVD severity in T2DM. Lp-PLA2 may be a novel biomarker diagnosing and evaluating CVD in T2DM.