A new heliquinomycin analogue with immunosuppressive activity from Streptomyces sp. Jys28

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Abstract

Heliquinomycin (1) and a new analogue 9′-methoxy-heliquinomycin (2) were isolated from the culture broth of Streptomyces sp. jys28. The structure of new analogue was elucidated by comprehensive analyses of HR-ESI-MS and NMR spectroscopic data. Among them, Heliquinomycin (1) showed immunosuppressive and antibacterial activities.

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Su, C., Liu, C., Wang, Y., Xiang, W. S., Zou, C. G., & Huang, S. X. (2019). A new heliquinomycin analogue with immunosuppressive activity from Streptomyces sp. Jys28. Records of Natural Products, 13(6), 456–461. https://doi.org/10.25135/rnp.123.18.12.1085

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