A novel asymmetric synthesis of cinacalcet hydrochloride

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Abstract

A novel route to asymmetric synthesis of cinacalcet hydrochloride by the application of (R)-tert-butanesulfinamide and regioselective N-alkylation of the naphthyl ethyl sulfinamide intermediate is described. © 2012 Arava et al; licensee Beilstein-Institut. License and terms: see end of document.

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Arava, V. R., Gorentla, L., & Dubey, P. K. (2012). A novel asymmetric synthesis of cinacalcet hydrochloride. Beilstein Journal of Organic Chemistry, 8, 1366–1373. https://doi.org/10.3762/bjoc.8.158

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