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Rbfox1 Mediates Cell-type-Specific Splicing in Cortical Interneurons

Neuron (2018) 100(4) 846-859.e7
DOI: 10.1016/j.neuron.2018.09.026
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Abstract

Wamsley et al. uncover a role of the splicing regulator Rbfox1 in promoting interneuron-specific connectivity in the developing neocortex. By differentially regulating alternative splicing profiles in PV+ and SST+ interneurons, Rbfox1 tailors their efferent connectivity.

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Wamsley, B., Jaglin, X. H., Favuzzi, E., Quattrocolo, G., Nigro, M. J., Yusuf, N., … Fishell, G. (2018). Rbfox1 Mediates Cell-type-Specific Splicing in Cortical Interneurons. Neuron, 100(4), 846-859.e7. https://doi.org/10.1016/j.neuron.2018.09.026

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