Arthrogryposis multiplex congenita

Abstract

Arthrogryposis multiplex congenita literally means multiple curved joints, occurring as a congenital anomaly in the newborn. The first description is ascribed to Otto in 1841 [1]. Sheldon in 1932 published the first detailed description in the United Kingdom and called the condition amyoplasia congenita emphasizing the lack of muscle development in this condition [2]. It is important to realize that arthrogryposis is a descriptive term and not an exact diagnosis. Hall who has made a special study of the genetics of the disorder pointed out that there are at least 150 possible diagnoses that can result in multiple curved joint deformities in the newborn child [3]. The reader is referred to Hall for a comprehensive discussion of the disorder [4]. © Springer-Verlag London Limited 2010.