Intestinal microbiota and cardiovascular diseases

Abstract

The article presents a review of publications in in Russian and foreign literature devoted to modern views on the role of intestinal microbial metabolites as risk factors for cardiovascular diseases. The technical capabilities of the last decade made it possible to accurately characterize the intestinal microbiota, which contributed to a deeper understanding of the processes occurring during the development of a number of diseases and to establish that the outcome of their treatment is affected by pronounced changes in the composition, diversity and metabolic activity of the human intestinal microbiota. A number of questions on the interaction of the intestinal microbiota and the host organism remain open. Further research on the relationship of the intestinal microbiota, its metabolic products with risk factors for cardiovascular diseases opens up unique opportunities in the treatment and prevention of diseases of the cardiovascular system using manipulative technologies with the composition of the microbiota and its function.