Thermal inactivation of bovine immunodeficiency virus

Abstract

Cell-associated bovine immunodeficiency virus (BIV) and cell-free BIV were subjected to increasing temperatures, including pasteurization conditions. To determine the effect of heat treatment on BIV viability, reverse transcriptase activity and infectivity of the heat-treated virus were assessed. BIV was inactivated by heating to 47°C for 30 min and by low- and high-temperature pasteurization conditions.