Intron mis-splicing: no alternative?

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Abstract

A recent report reveals widespread mis-splicing of RNA transcripts in eukaryotes, with mis-spliced RNA destroyed by nonsense-mediated mRNA decay. This striking inefficiency deepens the mystery of the proliferation and persistence of introns.

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Roy, S. W., & Irimia, M. (2008). Intron mis-splicing: no alternative? Genome Biology. https://doi.org/10.1186/gb-2008-9-2-208

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