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Book Chapter

Multicenter Trials

  • Friedman L
  • Furberg C
  • DeMets D
  • et al.
Springer International Publishing, (2015), 501-518
DOI: 10.1007/978-3-319-18539-2_21
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Abstract

A multicenter trial is a collaborative effort that involves more than one independent center in enrolling and following study participants. Multicenter randomized clinical trials have a long and rich history, with Hill [1] and Greenberg [2] providing general discussions of methods in the middle of the twentieth century.

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Friedman, L. M., Furberg, C. D., DeMets, D. L., Reboussin, D. M., & Granger, C. B. (2015). Multicenter Trials. In Fundamentals of Clinical Trials (pp. 501–518). Springer International Publishing. https://doi.org/10.1007/978-3-319-18539-2_21

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