Graft healing in ACL reconstruction: Can we enhance it in clinical practice?

Abstract

Surgical reconstruction of the anterior cruciate ligament (ACL) using tendon grafts is the current standard to treat the functionally ACL-deficient knee. The success of ACL reconstruction depends on a correct remodeling, reinnervation, and maturation of the graft used to replace the ACL. Remodeling and maturation of the graft affect directly the mechanical properties of the graft. Moreover, restoration of proprioception is equally as important as restoring mechanical stability of the knee. Restoration of proprioception is the result of reinnervation of the ACL graft.