Abstract
The two murine retroviral restriction genes, Fv-4 and Akvr-1, are very similar in their effects, distributions, ranges of action, and phenotypes. Akvr-1 has been shown to segregate independently in backcrosses with a variety of retroviral restriction loci, including Fv-1, Fv-2, Ril-1, and Ril-2. An allelism test cross of FRG (Fv-4R) X LCRR (Akvr-1R) hybrids mated to AKR mice failed to produce any viremic offspring. These results suggested that Akvr-1R and Fv-4R are alleles of a single locus, Fv-4, on mouse chromosome 12.
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CITATION STYLE
O’Brien, S. J., Berman, E. J., Estes, J. D., & Gardner, M. B. (1983). Murine retroviral restriction genes Fv-4 and Akvr-1 are alleles of a single locus. Journal of Virology, 47(3), 649–651. https://doi.org/10.1128/jvi.47.3.649-651.1983
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