Bone Mechanics and Cell Populations: Mathematical Description and Parametric Study of the Model

Abstract

In this paper we study a recently proposed mathematical model for the description of the mechanics of bone as well as bone remodeling processes and bone cell populations dynamics. We investigate the biological meaning and a suitable value for the numerical parameters of the model. To do so, we compare biological data with a systematic numerical investigation of the model. We also propose some corrections to the original model aimed at better describing the observed phenomena.