Cardiac cell replacement therapy with pluripotent stem cell derived cardiomyocytes

Abstract

This chapter tries to give an overview on cardiac cell replacement therapy with pluripotent stem cell derived cardiomyocytes. After a general introduction addressing concept, potential cell types and potential routes of administration, it highlights electrophysiology as well as engraftment and persistence of transplanted cardiomyocytes summarizing what has been achieved and what still needs further investigations.