Extraction and antimicrobial potential of secondary plant metabolites from artabotrys hexapetalus (linn. F.) Bhandari

Abstract

Plants are the important sources for several drugs. In recent years many drug formulations are based on plant products. The present study was carried out with an objective to investigate the antibacterial and antifungal potentials of leaves of Artabotrys hexapetalus Linn. belonging to the family Annonaceae. It is widely distributed throughout the southern part of the Asia and china. In the present study, methanolic extracts of leaves of Artabotrys hexapetalus Linn was evaluated for potential antimicrobial activity against medically important bacterial and fungal strains. The antimicrobial activity was determined in the extracts using agar well diffusion method. The antibacterial and antifungal activities of extracts (25, 50, 75 and 100 μg/ml) of Artabotrys hexapetalus were tested against ten human pathogenic bacteria; and four fungal strains. The results revealed that the remarkable inhibition of the microbial growth was shown against the tested organisms. Phytochemical analysis of the plant was also carried out. The microbial activity of the Artabotrys hexapetalus was due to the presence of various secondary metabolites. Hence, this plant can be further studied to discover bioactive natural products that may serve as lead molecules in the development of new pharmaceutically important compounds.