Testing for the presence of genetic mutations yields useful diagnostic, therapeutic, and prognostic information and has become the standard of care for a variety of hematologic and solid tumors. The majority of molecular tests use a polymerase chain reaction-based approach. The choice of test methodology depends on many factors, such as the type and frequency of mutation, anticipated test volume, tumor type, sample type and volume, cost of technology, and preexisting instruments.
CITATION STYLE
Patel, K. P., Galbincea, J., & Luthra, R. (2012). Mutation analysis in cancer. In Modern Clinical Molecular Techniques (pp. 261–279). Springer New York. https://doi.org/10.1007/978-1-4614-2170-2_18
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