Natural killer leukemia is a rare and highly aggressive neoplasm, is more common in young male patients and has a very poor prognosis, with a median survival of few weeks. We report a 17 years old male patient who developed, after an acute upper respiratory disease, a rapidly multiorganic failure with pancytopenia. Bone marrow aspiration and trephine biopsy showed an acute lymphoblastic leukemia. The immunophenotype and immunohistochemistry revealed a natural killer acute leukemia. The disease progressed rapidly and the patient died shortly after the diagnosis.
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Guerrero A, M., Lira V, P., Bertin C, P., Galleguillos V, M., & Ocqueteau T, M. (2005). Leucemia de células natural killer. Caso clínico. Revista Medica de Chile, 133(4), 457–460. https://doi.org/10.4067/s0034-98872005000400010