Two new glycosides from the soft coral Sinularia firma

Abstract

Two new glycosides, named Firmacosides A and B, together with known fatty esters, batyl alcohol, Δ5,20 sterol and sphingosine derivatives have been isolated from the soft coral Sinularia firma TIX-DUR. On the basis of spectroscopic analysis (1H-NMR, 13C-NMR, 1H-1H COSY, HMQC, HMBC and FAB-MS), Firmacoside A was established as hexadecanyl-1-O-α-D-arabinopyranosyloxy (1→4)-α-D-arabinopyranosyloxy (1→4)-α-D-arabinopyranoside (1), and firmacoside B was elucidated as docosanyl-1-O-α-D- arabinopyranosyloxy (1→4)-3-O-acetyl-α-arabinopyranosyloxy (1→4)-α-D-arabinopyranoside (2). © 2006 Pharmaceutical Society of Japan.