Effectiveness of Eugenol as An Antibacterial Toward Staphylococcus epidermidis

Abstract

Eugenol is generally used as raw materials of perfumes, but now eugenol was developed as an antioxidant, antifungal, antibacterial and antiseptic. This study aims to determine the effect of eugenol concentration and pH and the effectiveness of eugenol as an antibacterial against Staphylococcus epidermidis. The experiments were carried out at concentrations of 1%, 2%, 4%, 6% and 8% with pH 6, 7 and 8. Data were collected and analyzed by two-way ANOVA method with interaction level of 5% (α = 0.05). The results showed that eugenol has an antibacterial effect in inhibiting the growth of bacteria Staphylococcus Epidermidis and included in the category of strong to very strong antibacterial. The optimum yield diameter of the inhibitory zone is 22.27 mm, obtained at pH 8 and the concentration of eugenol is 8%.