Comparative study for success rate of vaginal birth after cesarean section following labor induction by two forms of vaginal dinosprostone: A pilot study

Abstract

Background: Cesarean delivery has become the most common major surgical procedure in many parts of the world. Induction of labor in women with prior ce-sarean delivery is an alternative to mitigate the rising cesarean rates. Objectives: To compare the VBAC success rate between two vaginal forms of dinopros-tone for labor induction in women with prior cesa-rean section. Material and Methods: A pilot study was conducted at a large Governmental Hospital, Dha-hran, Saudi Arabia, including 200 women with prior cesarean section and planned for labor induction. Participants were randomly allocated into two groups. Group A (n = 100) received dinoprostone 1.5 mg va-ginal tablet. Group B (n = 100) received 10 mg dino-prostone sustained release vaginal pessary. Primary outcome was vaginal delivery rate. Secondary outcomes included maternal and neonatal outcomes. Results: The dinoprostone vaginal tablet and dino-prostone vaginal pessary had a comparable vaginal delivery rate (67% and 64%, respectively; p = 0.78). The median patient satisfaction with the birth process was superior in the dinoprostone vaginal pessary group (p = 0.04). Maternal and neonatal outcomes were similar in both groups. Conclusion: Both forms of dinoprostone were effective methods for labor induction in women with prior cesarean section. However , the patient satisfaction with the birth process was in favor of the dinoprostone sustained release va-ginal pessary.