Retinoic acid-inducible gene (RIG)-I-like receptors (RLRs) are cytosolic RNA helicases that sense viral RNA and trigger signaling pathways that induce the production of type I interferons (IFNs) and proinf ammatory cytokines. RLRs recognize distinct and overlapping sets of viruses, but the mechanisms that dictate this specif city were unknown. A new study now provides evidence for size-based discrimination of double-stranded RNA (dsRNA) by RLRs and suggests how host cells recognize a variety of RNA viruses.
CITATION STYLE
Elias, S. J., Mohd Warip, M. N., Mansor, S., Muhamat Dawam, S. R., & Mansor, Ab. R. (2017). Experimental Model of Congestion Control Vehicular Ad Hoc Network Using OMNET++. In Proceedings of the International Conference on Computing, Mathematics and Statistics (iCMS 2015) (pp. 25–35). Springer Singapore. https://doi.org/10.1007/978-981-10-2772-7_3
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