Abstract
Elevated circulating cell-free DNA (CFD) levels were found in patients with cancer. The standard CFD assays are work-intensive and expensive. The aim was to evaluate in patients with cancer a new simple CFD assay. In mice inoculated with cancer cells, CFD levels correlated with tumor size. Compared with healthy subjects, 38 patients with colorectal cancer (CRC) had higher preoperative CFD levels (798 ± 409 vs 308 ± 256 ng/mL; P
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Czeiger, D., Shaked, G., Eini, H., Vered, I., Belochitski, O., Avriel, A., … Douvdevani, A. (2011). Measurement of circulating cell-free DNA levels by a new simple fluorescent test in patients with primary colorectal cancer. American Journal of Clinical Pathology, 135(2), 264–270. https://doi.org/10.1309/AJCP4RK2IHVKTTZV
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