Some Questions to Our Chinese Colleagues Pioneering Research Into Coronavirus Disease 2019 (COVID-19)

Abstract

A pandemic has developed, so physicians worldwide are particularly interested in the experiences of their Chinese Colleagues which are frequently cited. To assess the long-term pulmonary, cardiac, neurologic, and psychiatric consequences after COVID-19, the outcome of patients included in the early publications and the association with baseline findings is of particular interest. Thus, we review the methods of early Coronavirus disease 2019 (COVID-19) publications. Reports published before March 19th 2020, comprising >40 patients were included, considering especially cardiologic aspects. It remains unclear whether patients were described several times, or they were different patients. Only patients with confirmed COVID-19 were described, and no differences in findings of patients with initially suspected and later confirmed, or excluded infection. It remains unclear in how many cases information was missing, since missing values were not reported. Medication before hospital admission, level of education and occupation, household size and composition, weight or body mass index are lacking. No details about electrocardiographic findings are given. Patients still in follow-up, constituting the major part of observations, were excluded. The data should be re-analyzed. A comparison between confirmed and excluded cases could be carried out. By now, in November 2020, the reported patients will most probably have recovered. Thus, it would be possible to differentiate prognostic indicators more precisely. Laboratory tests and electrocardiograms could be analyzed in more detail to shed light on the spectrum of this disease and to solve some of the unanswered questions related with COVID-19.