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Molecular mechanisms by which rRNA mutations confer resistance to clindamycin

Antimicrobial Agents and Chemotherapy (2005) 49(4) 1553-1555
DOI: 10.1128/AAC.49.4.1553-1555.2005
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Abstract

The mechanisms by which rRNA mutations confer clindamycin resistance were examined in Mycobacterium smegmatis strains containing homogeneous populations of ribosomes with base substitutions at nucleotides A2058 and A2059. Computer graphic predictions based on structural studies correlate with the resistance phenotypes for six of seven strains with unique rRNA mutations. Copyright © 2005, American Society for Microbiology. All Rights Reserved.

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CITATION STYLE

APA

Poehlsgaard, J., Pfister, P., Böttger, E. C., & Douthwaite, S. (2005). Molecular mechanisms by which rRNA mutations confer resistance to clindamycin. Antimicrobial Agents and Chemotherapy, 49(4), 1553–1555. https://doi.org/10.1128/AAC.49.4.1553-1555.2005

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